We explore the history and modern complexities of ordinal outcomes in clinical trials, discussing their importance and the contentious debates surrounding their analysis.

An in-depth exploration of the HEALEY ALS Platform Trial's innovative design and impact on clinical trials.

Discover how the latest release of FACTS enhances clinical trial simulations with greater complexity, flexibility, and usability.

Adaptive design clinical trials offer flexibility, efficiency, and improved outcomes in medical research, but when should you explore their usage?

The Precision Promise platform trial is an adaptive study exploring multiple potential therapies for pancreatic cancer, with pamrevlumab recently advancing to the next stage after demonstrating a predictive probability of at least 35% for improved overall survival, highlighting the trial's innovative approach to efficiently identify effective treatments in a field with limited options.

Kert Viele's blog discusses the FDA's draft guidance on master protocols for drug and biological product development, highlighting key sections on trial design, randomization, control groups, informed consent, and regulatory considerations, while encouraging feedback from experts to enhance the guidance's effectiveness before the comment deadline of February 22.