Publications
Where expertise meets impact
Berry doesn’t just follow industry standards — we set them. Our team of award-winning statisticians, journal editors, and regulatory advisors leads the field in Bayesian and adaptive trial design. With research published in The New England Journal of Medicine, JAMA, and The Lancet, we’re driving innovation where it matters most.
Over 90% of our scientists published influential work this past year, advancing adaptive, Bayesian, and platform trial methodology. Our blend of academic rigor, regulatory insight, and real-world experience makes Berry a true authority in modern clinical trials.
Explore our most impactful peer-reviewed publications below.


JHEP Reports
Oncology
Meta-analysis
A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma
December 12, 2023
2023
doi: 10.1016/j.jhepr.2023.100982
JAMA
Infectious Disease
COVID-19
Platform
Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials
November 4, 2023
2023
doi: 10.1001/jama.2023.21407.
Annals of Neurology
Neuroscience
Rare Diseases
Historical Borrowing
Analysis of sodium phenylbutyrate and taurursodiol survival effect in ALS using external controls
October 9, 2023
2023
doi: 10.1002/acn3.51915
Clinical Infectious Disease
Infectious Disease
Platform
Early Oral Antibiotic Switch in Staphylococcus aureus Bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol
August 15, 2023
2023
doi: 10.1093/cid/ciad666.
Trials Journal
Methodology
Other
Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing
August 5, 2023
2023
doi.org/10.1186/s13063-023-07576-7
JAMA
Methodology
Stopping Rules
Futility in Clinical Trials
July 31, 2023
2023
doi: 10.1001/jama.2023.14111.

Science Direct
Methodology
Platform
NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls
July 31, 2023
2023
doi.org/10.1016/j.softx.2023.101437

Science Direct
Methodology
Platform
SIMPLE—A modular tool for simulating complex platform trials
July 30, 2023
2023
doi.org/10.1016/j.softx.2023.101515
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