Barbara Wendelberger is a Senior Statistical Scientist at Berry Consultants, where she focuses on innovative statistical approaches to address complex challenges in clinical trial design. She designs Bayesian adaptive clinical trials for numerous therapeutic areas and specializes in leveraging natural history data on biomarkers and clinical endpoints to model disease progression. Barbara is passionate about translating a deeper biological understanding of a disease to a more efficient and informative clinical trial, particularly in neurodegenerative and rare diseases. Before joining Berry Consultants in 2016, she earned her PhD from the University of Wisconsin. Her doctoral research focused on a Variational Bayesian method for estimating neural effective connectivity networks using information from multiple imaging modalities. Previously, Barbara was a member of the Genomics group at Los Alamos National Laboratory, participating in both sequencing technology and metagenomics research. Her research interests continue to focus on data-driven inference at the juncture between statistics, mathematics, biology, and medicine.